6TXV_1|Chains A, B|Transthyretin|Homo sapiens (9606)
>2KSW_1|Chain A|Oryctin|Oryctes rhinoceros (72550)
>3HRO_1|Chain A|Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2), also called Polycystin-2 or polycystic kidney disease 2(PKD2)|Homo sapiens (9606)
Let \(P_w(n)\) be the set of distinct subwords (intervals) in a word \(w\).
Let \(p_w(n)\) be the cardinality of \(P_w(n)\).
Let \(f(c)\) be the sequence in FASTA with 4-symbol Protein Data Bank code \(c\).
\(|P_{f(6TXV_1)}(2) \setminus P_{f(2KSW_1)}(2)|=78\),
\(|P_{f(2KSW_1)}(2) \setminus P_{f(6TXV_1)}(2)|=43\).
Let
\(
Z_k(x,y)=|P_x(k)\setminus P_y(k)|+|P_y(k)\setminus P_x(k)|
\)
be a LZ76 style (set of subwords) Jaccard distance numerator for \(P(k)\).Hydrophobic-polar version of Sequence 1:01111011011010101011101100110001011101000001010110000011011001010000010111101100010111010001100001111101000000111001
Pair
\(Z_2\)
Length of longest common subsequence
6TXV_1,2KSW_1
121
2
6TXV_1,3HRO_1
105
3
2KSW_1,3HRO_1
84
2
Newick tree
[
6TXV_1:60.74,
[
3HRO_1:42,2KSW_1:42
]:18.74
]
Let d be the
Otu--Sayood
distance d.
Let d1 be the Otu--Sayood distance d1. (This makes the 4TYN sequence AAAAAA a close match...)
A roughly speaking expected distance is \((0.85)(0.8)(\frac{182
}{\log_{20}
182}-\frac{66}{\log_{20}66})=39.1\)
Status
Protein1
Protein2
d
d1/2
Query variables
6TXV_1
2KSW_1
51
40
Was not able to put for d Was not able to put for d1
In notation analogous to
[Theorem 16, Kjos-Hanssen, Niraula and Yoon (2022)],
\[
\delta=
\alpha \mathrm{min} + (1-\alpha) \mathrm{max}=
\begin{cases}
d &\alpha=0,\\
d_1/2 &\alpha=1/2
\end{cases}
\]