6MXR_1|Chains A, C[auth H]|anti-VEGF-A Fab fragment bH1 heavy chain|Homo sapiens (9606)
>1WJV_1|Chain A|Cell growth regulating nucleolar protein LYAR|Mus musculus (10090)
>4GBD_1|Chains A, B|Putative uncharacterized protein|Pseudomonas aeruginosa (208964)
Let \(P_w(n)\) be the set of distinct subwords (intervals) in a word \(w\).
Let \(p_w(n)\) be the cardinality of \(P_w(n)\).
Let \(f(c)\) be the sequence in FASTA with 4-symbol Protein Data Bank code \(c\).
\(|P_{f(6MXR_1)}(2) \setminus P_{f(1WJV_1)}(2)|=126\),
\(|P_{f(1WJV_1)}(2) \setminus P_{f(6MXR_1)}(2)|=36\).
Let
\(
Z_k(x,y)=|P_x(k)\setminus P_y(k)|+|P_y(k)\setminus P_x(k)|
\)
be a LZ76 style (set of subwords) Jaccard distance numerator for \(P(k)\).Hydrophobic-polar version of Sequence 1:01011001111101110101001101101000110110011101101110101001000010010101010100000010101001010001100000111111011001101011010010001101111110000001101111011000110110101001110011001111100011001001101100011000010010001000010001010000001000000001
Pair
\(Z_2\)
Length of longest common subsequence
6MXR_1,1WJV_1
162
3
6MXR_1,4GBD_1
185
6
1WJV_1,4GBD_1
217
3
Newick tree
[
4GBD_1:10.60,
[
6MXR_1:81,1WJV_1:81
]:25.60
]
Let d be the
Otu--Sayood
distance d.
Let d1 be the Otu--Sayood distance d1. (This makes the 4TYN sequence AAAAAA a close match...)
A roughly speaking expected distance is \((0.85)(0.8)(\frac{315
}{\log_{20}
315}-\frac{79}{\log_{20}79})=74.7\)
Status
Protein1
Protein2
d
d1/2
Query variables
6MXR_1
1WJV_1
92
61
Was not able to put for d Was not able to put for d1
In notation analogous to
[Theorem 16, Kjos-Hanssen, Niraula and Yoon (2022)],
\[
\delta=
\alpha \mathrm{min} + (1-\alpha) \mathrm{max}=
\begin{cases}
d &\alpha=0,\\
d_1/2 &\alpha=1/2
\end{cases}
\]